POM’s Published Studies

POM’s Published Studies

Effects of Pomegranate Juice and Extract Polyphenols on Platelet Function

Journal of Medicinal Food,

by F.M. Pulcinelli, et al.

Pomegranate Polyphenols Down-Regulate Expression of Androgen-Synthesizing Genes in Human Prostate Cancer Cells Overexpressing the Androgen Receptor

Journal of Nutritional Biochemistry,

by D. Heber, et al.

Pomegranate (Punica granatum) Supplements: Authenticity, Antioxidant and Polyphenol Composition

Journal of Functional Foods,

by Reed, et al.

A Study to Measure the Glycaemic Index Value of Pomegranate Juice

The School of Molecular and Microbial Bio-sciences at Sydney University,

by Glycaemic Index Research Service

Ellagitannin Consumption Improves Strength Recovery 2-3 d after Eccentric Exercise

The American College of Sports Medicine,

by Justin R. Trombold

Effects of Consumption of Pomegranate Juice on Carotid Intima-Media Thickness in Men and Women at Moderate Risk for Coronary Heart Disease

American Journal of Cardiology, 2009,

by M.H. Davidson et al.,

Absence of Pomegranate Ellagitannins in the Majority of Commercial Pomegranate Extracts: Implications for Standardization and Quality Control

Journal of Agricultural and Food Chemistry, 2009

by Yanjun Zhang, David Wang, Ru-Po Lee, Susanne M. Henning, and David Heber

Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis

Nutrition, 2008

by T.M. Haqqi, et al.

Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin

Experimental Dermatology, 2009

by H. Mukhtar, et al.

Inhibition of UVB-mediated Oxidative Stress and Markers of Photoaging in Immortalized HaCaT Keratinocytes by Pomegranate Polyphenol Extract POMx

Photochemistry and Photobiology, 2007

by H. Mukhtar, et al.

Pomegranate’s Ancient Roots to Modern Medicine, Pomegranates: Ancient Roots to Modern Medicine

Taylor and Francis, 2006

by M.P. Warren, et al.

Safety and Antioxidant Activity of a Pomegranate Ellagitannin-Enriched Polyphenol Dietary Supplement in Overweight Individuals with Increased Waist Size

Journal of Agricultural and Food Chemistry, 2007

by D. Heber, et al.

Pomegranate Juice Does Not Impair Clearance of Oral or Intravenous Midazolam, a Probe for Cytochrome P450-3A Activity: Comparison With Grapefruit Juice

Journal of Clinical Pharmacology, 2007

by D.J. Greenblatt, et al.

Pomegranates and Prostate Health: A Research Report

PCRI Insights, 2008

by M. Dreher, et al.

Scientific and Clinical Monograph for POM Wonderful Pomegranate Juice

American Botanical Council, 2008

by A. McCutcheon, Udani, and Brown, et al.

Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: Studies in atherosclerotic mice and in humans

Drugs Under Experimental and Clinical Research XXVIII, 2003

by M. Aviram, et al.

Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells

Journal of Inflammation, 2009

by T.M. Haqqi, et al.

Antioxidant, Antimalarial and Antimicrobial Activities of Tannin-Rich Fractions, Ellagitannins and Phenolic Acids from Punica granatum L.

Planta Medica, 2007

by D. Ferreira, et al.

Pomegranate seed oil consumption during a period of high-fat feeding reduces weight gain and reduces type 2 diabetes risk in CD-1 mice

British Journal of Nutrition, 2008

by B.K. McFarlin, et al.

Pomegranate juice sugar fraction reduces macrophage oxidative state, whereas white grape juice sugar fraction increases it

Atherosclerosis, 2006

by M. Aviram, et al.

Consumption of Wonderful Variety Pomegranate Juice and Extract by Diabetic Patients Increases Paraoxonase 1 Association with High-Density Lipoprotein and Stimulates Its Catalytic Activities

Journal of Agricultural and Food Chemistry, 2008

by M. Aviram, et al.

Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages

Atherosclerosis, 2006

by M. Aviram, et al.

International Multidimensional Authenticity Specification (IMAS) Algorithm for Detection of Commercial Pomegranate Juice Adulteration

Journal of Agricultural and Food Chemistry, 2009

by D. Heber, et al.

Pomegranate (Punica granatum) supplements: authenticity, antioxidant and polyphenol composition

Journal of Functional Foods, 2009

by Reed, et al.

Development of a novel pomegranate standard and new method for the quantitative measurement of pomegranate polyphenols

Journal of Science of Food and Agriculture, 2009

by Martin et al., 2009.

Maternal Dietary Supplementation with Pomegranate Juice Is Neuroprotective in an Animal Model of Neonatal Hypoxic-Ischemic Brain Injury

Pediatric Research, 2005

by D.M. Holtzman, et al.

Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer’s disease

Neurobiology of Disease, 2006

by D.M. Holtzman, et al.

Effects of Pomegranate Juice and Extract Polyphenols on Platelet Function

Journal of Medicinal Food, 2009

by F.M. Pulcinelli, et al.

Oxidative Stress in Arteriogenic Erectile Dysfunction: Prophylactic Role of Antioxidants

Journal of Urology, 2005

by K.M. Azadzoi, et al.

Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study

International Journal of Impotence Research, 2007

by H. Padma-Nathan, et al.

Effects of Pomegranate Juice Consumption on Myocardial Perfusion in Patients With Coronary Heart Disease

American Journal of Cardiology, 2005

by D. Ornish, et al.

Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure

Atherosclerosis, 2001

by M. Aviram, et al.

Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR and AP-1 pathway activation

Atherosclerosis, 2007

by M. Aviram, et al.

Pomegranate Phenolics from the Peels, Arils, and Flowers Are Antiatherogenic: Studies in Vivo in Atherosclerotic Apolipoprotein E-Deficient (E0) Mice and in Vitro in Cultured Macrophages and Lipoproteins

Journal of Agricultural and Food Chemistry, 2008

by M. Aviram, et al.

Effects of a Pomegranate Fruit Extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis

Cardiovascular Research, 2007

by C. Napoli, et al.

Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells

Nitric oxide, 2006

by C. Napoli, et al.

Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

Proceedings of the National Academy of Sciences, 2005

by L.J. Ignarro et al.

Pomegranate Byproduct Administration to Apolipoprotein E-Deficient Mice Attenuates Atherosclerosis Development as a Result of Decreased Macrophage Oxidative Stress and Reduced Cellular Uptake of Oxidized Low-Density Lipoprotein

Journal of Agricultural and Food Chemistry, 2006

by M. Aviram, et al.

The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats

Nitric oxide, 2007

by C. Napoli, et al.

Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages

Journal of Nutritional Biochemistry, 2005

by M. Aviram, et al.

Pomegranate Juice Supplementation to Atherosclerotic Mice Reduces Macrophage Lipid Peroxidation, Cellular Cholesterol Accumulation and Development of Atherosclerosis

Journal of Nutrition, 2001

by M. Aviram, et al.

Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation

Clinical Nutrition, 2004

by M. Aviram, et al.

Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice

American Journal of Clinical Nutrition, 2000

by M. Aviram, et al.

Ellagitannin-rich pomegranate extract inhibits angiogenesis in prostate cancer in vitro and in vivo

International Journal of Oncology, 2008

by D. Heber, et al.

Pomegranate extract inhibits androgen-independent prostate cancer growth through a nuclear factor-KB-dependent mechanism

Molecular Cancer Therapy, 2008

by D. Heber, et al.

Pomegranate Ellagitannin-Derived Metabolites Inhibit Prostate Cancer Growth and Localize to the Mouse Prostate Gland

Journal of Agricultural and Food Chemistry, 2007

by D. Heber, et al.

Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor

Journal of Nutritional Biochemistry, 2008

by D. Heber, et al.

Phase II Study of Pomegranate Juice for Men with Rising Prostate-Specific Antigen following Surgery or Radiation for Prostate Cancer

Clinical Cancer Research, 2006

by A. Pantuck, et al.

In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice

Journal of Nutritional Biochemistry, 2005

by D. Heber, et al.

Pomegranate Juice, Total Pomegranate Ellagitannins, and Punicalagin Suppress Inflammatory Cell Signaling in Colon Cancer Cells

Journal of Agricultural and Food Chemistry, 2006

by D. Heber, et al.

Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice

Clinica Chimica Acta, 2004

by D. Heber, et al.

Pomegranate Juice Ellagitannin Metabolites Are Present in Human Plasma and Some Persist in Urine for Up to 48 Hours

Journal of Nutrition, 2006

by D. Heber, et al.

Pomegranate Juice and Extracts Provide Similar Levels of Plasma and Urinary Ellagitannin Metabolites in Human Subjects

Journal of Medicinal Food, 2008

by D. Heber, et al.

Comparison of Antioxidant Potency of Commonly Consumed Polyphenol-Rich Beverages in the United States

Journal of Agricultural and Food Chemistry, 2008

by N. Seeram, et al.

Antioxidant Activity of Pomegranate Juice and Its Relationship with Phenolic Composition and Processing

Journal of Agricultural and Food Chemistry, 2000

by A.A. Kader, et al.

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